polymorphisms in melanocortin receptor 1 gene in goat breeds: a window for coat color controling mechanism

نویسندگان

a. javanmard

b. arafnajad

r. abdollahi arpanahi

m.h. moradi

چکیده

the broad goal of this research was to examine the nature of the melanocortin receptor 1 (mc1r) locus on the coat color phenotype of seven goat breeds with different color coat. blood samples were collected from five iranian indigenous (khalkhal, markhor, naeini, najdi and tali) and two exotic (cashmere and saanen) goat breeds. polymerase chain reaction restriction fragment length polymorphism (pcr-rflp) technique and dna sequencing were used to detect polymorphism of themc1rgene. digestion of polymerase chain reaction products with eari revealed two alleles of a and b and three genotypes of aa, ab and bb. the observed allele size was similar to previous reports. the genotype and gene frequencies for each breed were determined and shown to be variable among the breeds. in the goat breeds with black / brown coat color, aa genotype showed a higher frequency than white color goat breeds. in this aspect, tali had only aa and ab genotypes and cashmere had ab and bb genotypes. comparison of genotype frequencies using χ2 test showed significant (p

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منابع مشابه

Polymorphisms in Melanocortin Receptor 1 Gene in Goat Breeds: A Window for Coat Color Controling Mechanism

The broad goal of this research was to examine the nature of the Melanocortin receptor 1 (MC1R) locus on the coat color phenotype of seven goat breeds with different color coat. Blood samples were collected from five Iranian indigenous (Khalkhal, Markhor, Naeini, Najdi and Tali) and two exotic (Cashmere and Saanen) goat breeds. Polymerase chain reaction restriction fragment length polymorphism ...

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ISSN: 1937-9056 Copyright © 2008 Answers in Genesis. All rights reserved. Consent is given to unlimited copying, downloading, quoting from, and distribution of this article for non-commercial, non-sale purposes only, provided the following conditions are met: the author of the article is clearly identified; Answers in Genesis is acknowledged as the copyright owner; Answers Research Journal and ...

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عنوان ژورنال:
iranian journal of applied animal science

ناشر: islamic azad university - rasht branch

ISSN 2251-628X

دوره 5

شماره 4 2015

میزبانی شده توسط پلتفرم ابری doprax.com

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